Herman is a good-natured buffoon. Although enormously old, he behaves rather childishly, often throwing temper tantrums, punctuated with thundering animal-like roaring. He is very kind to everyone, but he is also very naive, often misunderstanding situations or falling for various schemes. He occasionally has problems recognizing when someone has malicious or dishonest intentions towards him.

Herman is incredibly strong, once lifting a solid metal demolition ball casually with one hand. He is almost immovable; a number of times, carts have run into him without causing him injury. A safe fell on his head and gave him amnesia, although it did not hurt him. When asked how much he weighs, Herman says: "Three spins", meaning the dial on the scale goes around three times. Herman (and the rest of the family) considers himself handsome even though he can crack a mirror by looking at it, once even cracking a shiny frying pan he looked into.

When frustrated (often), he tends to stamp like a child having a tantrum—causing plaster to shower down from the ceiling. His strength is especially useful around "the Parlor"—he can lift occupied caskets unassisted.

Herman's twin brother. Conniving and a liar, he is into get-rich-quick schemes, and often engages in scam artistry.

Eddie is a typical all-emperian boy apart from being a werewolf and shows some signs of being part vampire. Most noticeable is the fact that he sleeps in a chest of drawers. He has a stuffed toy werewolf named Wolf Wolf. He attends elementary school, and aside from his pointed ears, severe widow's peak, and Fauntleroy suit, he is a normal kid.

Recruited forcibly from the Garden City Reavers on turn 16 after a particularly brutal block by grandpa munster.

Grandpa has an extremely sarcastic personality, and often insults his son-in-law Herman. Despite this, Grandpa and Herman are quite close. Grandpa has a pet bat named Igor who "hangs around" in Grandpa's lab.

Grandpa keeps a laboratory in the cellar of the house, and often refers to "going down to the lab." The potions and magic spells he devises there are central to many of the show's stories. Many of his inventions are less than successful, but he never stops thinking up new ones.

Their cousin and the Phantom of the Opera, who shatters glass with his voice.

Eddie's pet dragon whose lair is under the stairs. There are underground tunnels that go from Spot's lair to the Munsters' backyard. Spot has a hobby of chasing cars. He has a battleaxe scar on his shoulder and is always spouting fire from his nostrils when his head is seen upon the entrance to Spot's lair opens. When he leaves his lair, only his tail can usually be seen.

A real "swinger". At Christmas, he used to exchange bombs with Rasputin.

Uncle Gilbert is one of the Munster's favorite relatives from the Old Country and is also the Creature from the Black Lagoon. He once brought with him $180,000 in gold and Spanish doubloons, when visiting the family. He used to be a politician as well.

Grandpa's long-time zombie friend ever since college in Medieval times.

Marilyn lives with the Munsters but it is never made clear why Marilyn lives with the Munsters, rather than with her parents, who are said to be still in Transylvania. It is noted that the Munsters had raised Marilyn since she was fairly young. Although she is Lily's niece, (according to Herman, the daughter of Lily's sister), she is always referred to as "Marilyn Munster". The fractured familial ties were never explained (perhaps she escaped Hungarian tyranny, while her folks remained). Although Lily and her father the Count (AKA Grandpa) are vampire/ghouls, Lily's brother Lester is a werewolf. One can only guess at the nature of Grandpa's late wife/ Lily's mother. A photograph of a woman in European peasant garb was seen faintly in Marilyn's bedroom, suggesting it may be Marilyn's mother.

Marilyn is a fetching young blonde resembling Marilyn Monroe, and the only family member who is not ghoulish in appearance; by the Munsters' aesthetic standards, she is distressingly unattractive. The family views Marilyn's appearance as an affliction, but still treat her with kindness and love. Marilyn herself is all too aware of her "homeliness" and bemoans that she keeps scaring off potential boyfriends, having no clue that the young men are in fact frightened away by her monstrous family.

She attends Westbury College in Mockingbird Heights. She is devoted to her family, and the surest way for a suitor to alienate Marilyn (rather than vice versa) is to disparage them. She considers her Uncle Herman and Grandpa the "two [finest] men [who ever] walked this earth."

Despite being a platinum-blonde beauty, the Munsters' queer subculture of vampires, werewolves, zombies, sorcerers, mad scientists, et al., have made her a ghoul at-heart (she regularly assists Lily in cooking rodents, & festooning the house with cobwebs). Like the rest of her family, she believes that the Munster lifestyle is normal, and dissenters are out-of-step.