René Descartes (March 31, 1596 – February 11, 1650), also known as Cartesius, was a noted French philosopher, mathematician, and scientist. Dubbed the "Founder of Modern Philosophy" and the "Father of Modern Mathematics," he ranks as one of the most important and influential thinkers of modern times. For good or bad, much of subsequent western philosophy is a reaction to his writings, which have been closely studied from his time down to the present day. Descartes was one of the key thinkers of the Scientific Revolution in the Western World. He is also honoured by having the Cartesian coordinate system used in plane geometry and algebra named after him.

Descartes frequently contrasted his views with those of his predecessors. In the opening section of the Passions of the Soul, he goes so far as to assert that he will write on his topic "as if no one had written on these matters before". Nevertheless many elements of his philosophy have precedents in late Aristotelianism, the revived Stoicism of the 16th century, or in earlier philosophers like Augustine. In his natural philosophy, he differs from the Schools on two major points: first, he rejects the analysis of corporeal substance into matter and form; second, he rejects any appeal to ends—divine or natural—in explaining natural phenomena. In his theology, he insists on the absolute freedom of God’s act of creation.

Descartes was a major figure in 17th century continental rationalism, later advocated by Baruch Spinoza and Gottfried Leibniz, and opposed by the empiricist school of thought, consisting of Hobbes, Locke, Berkeley, and Hume. Leibniz, Spinoza and Descartes were all versed in mathematics as well as philosophy, and Descartes and Leibniz contributed greatly to science as well. As the inventor of the Cartesian coordinate system, Descartes founded analytic geometry, that bridge between algebra and geometry crucial to the invention of the calculus and analysis. Descartes' reflections on mind and mechanism began the strain of western thought that much later, impelled by the invention of the electronic computer and by the possibility of machine intelligence, blossomed into, e.g., the Turing test. His most famous statement is Cogito ergo sum (French: Je pense, donc je suis or in English: I think, therefore I am), found in §7 of Principles of Philosophy (Latin) and part IV of Discourse on Method (French).