Medusa belongs to the race of Inhumans, a species of prehistoric earthlings mutated by the Terrigen Mists. Medusa possesses a long, thick head of red hair, every strand of which has greater tensile strength, modulus of elasticity, and shear resistance than an iron wire of the same thickness (average hair diameter: .045 inches), as well as the psychokinetic ability to animate her hair for a number of feats including using her hair to lift and move heavy weights (up to 1.6 tons). A portion of her hair must be used to anchor the rest at these greater weights, so that more than her scalp/skull is used as a brace.

Medusa uses her hair to pick up and hold on to the ball as if she had SURE HANDS. She also uses it to PASS the ball to her team-mates.