Fozzie Bear is The Muppet Show's resident comedian. He's an orange-brown, fuzzy Muppet bear who tells bad jokes, usually punctuated with his catchphrase, "Wocka wocka wocka!" He also often says "AaaAAAAaaah" when he tells the jokes, which somewhat serves the same purpose as "Wocka wocka." Fozzie is also best friends with Kermit, although they occasionally have differences of opinion.

During the first season of The Muppet Show, Fozzie's monologues usually consisted of Fozzie telling simple setup/punchline jokes, while being heckled by his mother's old friends, Statler and Waldorf. After the first season, most of his monologues relied on gimmicks such as telling jokes on roller skates. A common schtick in many episodes is that Fozzie would attempt to imitate the guest star's most famous act to attempt to emulate their success, only to comically fail completely at the attempt. For instance, Edgar Bergen inspired him to try ventriloquism while stage magician Doug Henning inadvertently convinced Fozzie to try his hand at being a magician. Fozzie also told a joke during the opening sequence of every episode during the first season.

In Jim Henson: The Works, Christopher Finch wrote: "One of the biggest problems [with the first season] was with Fozzie Bear. Fozzie was crucial to The Muppet Show because he was conceived as Frank Oz's main character, and the success of the show would depend to a significant degree on Frank having the opportunity to display the full range of his virtuoso performance and comedic skills.

"It was logical to have a comedian as a primary character on The Muppet Show, particularly once the Muppet Theater had been established as its basic setting. And given the spirit of the Muppets, it was almost inevitable that he would be a bad comedian. The problem with Fozzie was that his bad jokes and failure to win over an audience provoked more embarrassment than sympathy. For instance in episode 122, Fozzie gets so fed up with the heckling that he demands everyone but true Fozzie fans leave the auditorium. As a result, the seats are left completely empty; even Fozzie's own cousin leaves; Fozzie departs the stage almost in tears.

"Jerry Juhl and Frank Oz gradually transformed Fozzie by building up the positive aspects of his personality. They allowed his perpetual optimism to offset his onstage failures until he became a more rounded character. Fozzie's virtues ultimately made his ineptness acceptable -- and even endearing. So successful was this metamorphosis that he became one of the most popular of all the Muppets."

As Brian Henson notes in a generic Muppet Show introduction, "Fozzie is always telling terrible jokes, but he's just trying so hard you've got to love him."